WNK Signaling Inhibitors as Potential Antihypertensive Drugs
نویسندگان
چکیده
منابع مشابه
Virtual Screening of CDK9 Inhibitors as Potential Anti Cancer Drugs
Cell cycle inhibition is important hallmark of anti cancer research. CDKs are divided into two types based on their Cell cycle controlling and transcriptional control. CDK 9, a transcriptional regulator serves as potential drug target. Only few drugs are under clinical trials phase 1/2/3 of CDK 9 inhibitory potential. 3BLR (pdb id) is used as docking target. Virtual screening is carried out bas...
متن کاملAldose Reductase Inhibitors as Potential Therapeutic Drugs of Diabetic Complications
Diabetes mellitus has become a major health threat as a global rise in it has been seen. The chronic disease has afflicted over 171 million people worldwide in 2000 and the incidence is expected to grow steadily to 366 million by 2030. As of May 2008, an estimated 92 million adults in China of the most populous country were living with diabetes and 148 million adults with prediabetes [1]. Diabe...
متن کاملRecent Developments of Carbonic Anhydrase Inhibitors as Potential Drugs
1Department of Pharmaceutical Sciences and Centre for Advanced Drug Research, COMSATS Institute of Information Technology, Abbottabad, Pakistan 2Department of Chemistry, Forman Christian College (A Chartered University), Ferozepur Road, Lahore 54600, Pakistan 3Division of Biophysics, Department of Basic Medical Sciences, School of Medicine, Bahçeşehir University, Turkey 4Institute of Biostructu...
متن کاملNovel proteasome inhibitors as potential drugs to combat tuberculosis.
Mycobacterium tuberculosis is one of the most notorious killers worldwide. These pathogens have evolved to infect human beings in a so-called dormant form that is extremely difficult to treat. New work, however, suggests that mycobacterial proteasomes, multicomponent structures that protect the microbe from damaging effects of nitric oxide generated by the host, can be selectively and specifica...
متن کاملDrugs/Antibiotics as potential corrosion inhibitors for Metals - A Review
Corrosion protection of metals and alloys is a prime activity of technical, economic, environmental, and aesthetical significance. The use of inhibitors is one of the best choice of combating metals and alloys against detoriation against environmental impact. The toxicity of organic and inorganic corrosion inhibitors to the environment has provoked the search for ecofriendly corrosion inhibitor...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ChemMedChem
سال: 2017
ISSN: 1860-7179
DOI: 10.1002/cmdc.201700425